It kicked off at noon in front of City Hall and traveled six blocks down Main Street to the Statehouse.
Gov. Nikki Haley issued a proclamation declaring Friday is Gamecock Baseball Back-to-Back National Champions Day.
US Senator Lindsey Graham's resolution congratulating the USC baseball team also passed the Senate.
The team had already been honored with a party at Colonial Life Arena. The governor also had a Gamecocks flag flown atop the Statehouse dome the day after South Carolina clinched its second straight national title with a 5-2 win over Florida on Tuesday night.
The city estimated about 40,000 people came to last year's parade down the same route.
Copyright 2011 WIS. All rights reserved. AP contributed to this report.